The members of this section focus on the basic processes in biological aging. They work in different specialist fields in clinical medicine, clinical chemistry, biochemistry, physiology, anatomy, biology, biophysics, immunology, molecular biology, genetics and other areas.
Experimental approaches followed by members of this section are applied in the following areas:
- Longitudinal studies on the process of aging and influences on human aging
- Cohort and cross-sectional studies to examine the aging process in animals
- In vitro examination of aging processes in cell and tissue cultures of animal and human origin. The focus is on studies regarding the impact of growth factors, hormones, diet, oxidants, antioxidants and others. Also the effects of illnesses as well as of genetic factors on cell aging are assessed in vitro.
- Moleculobiological and moleculargenetic research investigating aging-related and aging-regulating processes in DNA replication, RNA transcription (and maturation), the cytoplasm transport of mRNA, the hormone-induced transfer of signals and other aspects in animal and human cells.
The biology of aging as basic research makes a vital contribution when it comes to understanding growth and aging mechanisms in cells, tissues, organs and organisms. These insights constitute the basis on which scientifically substantiated methods to prevent or to treat aging processes as well as geriatric diseases can be created.